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Endocrine Abstracts

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ea0015p288 | Reproduction | SFEBES2008

Association of variants within the fat mass and obesity-associated (FTO) gene and polycystic ovary syndrome

Barber Thomas , Bennett Amanda , Groves Christopher , Sovio Ulla , Ruokonen Aimo , Martikainen Hannu , Pouta Anneli , Hartikainen Anna-Liisa , Elliott Paul , Lindgren Cecilia , Freathy Rachel , Koch Kirsten , Ouwehand Willem , Karpe Fredrik , Conway Gerard , Wass John , Jarvelin Marjo-Riitta , Franks Stephen , McCarthy Mark

Background: Obesity plays an important role in the aetiology of polycystic ovary syndrome (PCOS). Variants in the fat-mass and obesity-associated (FTO) gene have recently been shown to influence adiposity and predispose to common obesity (Frayling et al., Science 2007 316 889–894).Aim: Our aim was to establish whether FTO variants are also implicated in PCOS-susceptibility.Methods: A genetic ...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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